发明名称 |
CONJUGATES FORMED FROM HEAT SHOCK PROTEINS AND OLIGO- OR POLYSACCHARIDES |
摘要 |
A conjugate compound comprises at least one heat shock protein or portion thereof including at least one immunostimula- tory domain and at least one capsular oligosaccharide or polysaccharide of a pathogenic bacteria. The compound comprises oli- gosaccharides of the Meningococci C (MenC) group and a heat shock protein selected from M. bovis BCG GroEl-type 65kDa hsp (hspR65); recombinant M. tuberculosis DnaK-type 70kDa hsp (hspR70) and a heat shock protein from H. pylori. The conju- gate compounds are useful in the preparation of vaccines to prevent bacteria l infection.
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申请公布号 |
CA2131551(C) |
申请公布日期 |
2003.05.20 |
申请号 |
CA19932131551 |
申请日期 |
1993.03.08 |
申请人 |
BIOCINE S.P.A. |
发明人 |
VITI, STEFANO;NORELLI, FRANCESCO;RAPPUOLI, RINO;COSTANTINO, PAOLO |
分类号 |
C12N15/09;A61K38/00;A61K39/00;A61K39/095;A61K39/385;A61K47/48;A61P31/04;A61P37/04;C07K14/195;C07K14/205;C07K14/35;C07K14/41;C07K19/00;C08B37/00;C12P21/02;(IPC1-7):A61K39/39;A61K39/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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