发明名称 |
Cadherin-like asymmetry protein-1, and methods for its use |
摘要 |
The present invention relates to molecules involved in cell-cell interactions in the immune system. In particular, the invention relates to a cell surface protein which contains certain classical cadherin characteristics, but it exhibits an apical distribution pattern on the surface of lymphocytes. The membrane location of this molecule correlates with the contact interface between T and B cells, and antibodies against an extracellular domain of this protein disrupt T cell/B cell interactions.
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申请公布号 |
US6565848(B1) |
申请公布日期 |
2003.05.20 |
申请号 |
US20000546934 |
申请日期 |
2000.04.11 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
LU PETER S.;DAVIS MARK M. |
分类号 |
C12N15/09;A61K31/711;A61K35/76;A61K38/00;A61K39/395;A61K48/00;A61P3/10;A61P17/00;A61P19/02;A61P25/00;A61P29/00;A61P37/02;C07K14/705;C07K16/28;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02;C12P21/08;C12Q1/02;(IPC1-7):A61K39/395 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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