发明名称 |
Immortal cell line derived from grouper Epinephelus coioides and its applications therein |
摘要 |
The present invention describes (1) an immortal cell line derived from grouper and a method for establishing the cell line; (2) methods for mass producing and purifying aquatic viruses using the immortal cell line from grouper; (3) an anti-NNV antibody and a method for producing the anti-NNV antibody; and (4) a vaccine of NNV and a method for protecting fish against NNV infection. The present immortal cell line is derived from the grouper and is susceptible to the viral families of Birnaviridae such as Infectious Pancreatic Necrosis Virus (IPNV); Herpesviridae such as Eel Herpes Virus Formosa (EHVF); Reoviridae such as Hard Clam Reovirus (HCRV); and Nodaviridae such as Nervous Necrosis Virus (NNV).
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申请公布号 |
US6566117(B2) |
申请公布日期 |
2003.05.20 |
申请号 |
US20010998212 |
申请日期 |
2001.12.03 |
申请人 |
NATIONAL SCIENCE COUNCIL |
发明人 |
CHI SHAU-CHI |
分类号 |
A61P31/12;C07K16/08;C12N7/02;C12P21/08;C12Q1/02;C12Q1/70;G01N33/569;(IPC1-7):C12N7/00 |
主分类号 |
A61P31/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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