发明名称 |
Cyclin dependent kinase mutants, and diagnostic and therapeutic uses related thereto |
摘要 |
The present invention relates to the discovery in eukaryotic cells, particularly mammalian cells, of mutant cyclin dependent kinase (CDK) proteins. These proteins fail to bind to CDK-inhibitory proteins and thus lead to aberrant cell growth. Herein, screening assays are described to identify CDK mutant proteins and the uses of these mutant proteins as tumor vaccines is described.
|
申请公布号 |
US6566054(B1) |
申请公布日期 |
2003.05.20 |
申请号 |
US19960706322 |
申请日期 |
1996.08.30 |
申请人 |
COLD SPRING HARBOR LABORATORY |
发明人 |
BEACH DAVID H.;SERRANO MANUEL |
分类号 |
C07K14/47;C07K16/18;C12N9/12;C12N15/85;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C07K14/47 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|