| 摘要 |
FIELD: medicine, infectious diseases. SUBSTANCE: vaccine represents the combination of antigens of opportunistic microorganisms with high-molecular synthetic carrier as N-hydroxy-1,4-ethylene piperazine and N-(carboxyethyl)-1,4-ethylene piperazinium bromide of molecular mass 30 000-120 000 Da with ratio antigens to carrier = 1:(5-50), respectively. The compound is represented as conjugate or prepared by complex-formation reaction. Invention can be used for prophylaxis and treatment of patients with suppurative-septic diseases. EFFECT: enhanced immunogenicity of vaccine. 4 cl, 3 dwg, 3 tbl, 5 ex |
