发明名称 |
New double-stranded oligonucleotides, useful e.g. for treatment and diagnosis of tumors, comprise complementary strands with single-stranded overhangs |
摘要 |
Double-stranded oligonucleotides (I) consisting of two complementary strands (Ia; Ib), each having at one of their 3' and 5' ends 1-5 unpaired nucleotides, forming single-stranded overhangs, are new. One of (Ia) and (Ib) is complementary to a target sequence, of DNA or RNA, that is to be specifically repressed.
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申请公布号 |
FR2832154(A1) |
申请公布日期 |
2003.05.16 |
申请号 |
FR20010014549 |
申请日期 |
2001.11.09 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS |
发明人 |
HAREL BELLAN ANNICK;AIT-SI-ALI SLIMANE;CABON GEORGET FLORENCE;CHAUCHEREAU ANNE;DAUTRY FRANCOIS |
分类号 |
C12N15/09;A61K31/7105;A61K31/711;A61K38/00;A61K48/00;A61P9/10;A61P9/14;A61P17/06;A61P19/02;A61P25/00;A61P27/02;A61P29/00;A61P31/00;A61P31/12;A61P31/18;A61P35/00;A61P43/00;C12N15/113 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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