| 摘要 |
2-Amino-4-heteroarylethyl thiazoline derivatives (I), their racemates, enantiomers, and diastereoisomers, their mixtures, tautomers and salts. 2-Amino-4-heteroarylethyl thiazoline derivatives of formula (I), their racemates, enantiomers, and diastereoisomers, their mixtures tautomers and salts. Het = 2-thienyl, 3-thienyl, 2-pyrimidyl, 5-pyrimidyl, 2-pyridyl, 3-pyridyl, 4-pyridyl, 2-thiazolyl, 4-thiazolyl, or 5-thiazolyl. Independent claims are also included for: (1) Preparation of (I); (2) Preparation of an intermediate of formula (II); and (3) 3 Intermediates: N-(tert-butyl)-N'-((1R)-2-hydroxy-1-(2-thien-3-ylethyl)ethyl) thiourea, (2R)-2-amino-4-(3-thienyl)-1-butanol hydrochloride and tert-butyl (4R)-2,2-dimethyl-4-(2-thien-3-ylethyl)oxazolidine-3-carboxylate. |
