发明名称 |
Denaturat stable and/or protease resistant, chaperone-like oligomeric proteins, polynucleotides encoding same, their uses and methods of increasing a specific activity thereof |
摘要 |
Novel denaturant-stable, protease resistant, homo-oligomeric proteins, also referred to herein as stable proteins (SPs), having chaperone-like activity; methods of production and purification of SPs; nucleic acids encoding SPs; methods of isolating nucleic acids encoding SPs; antibodies recognizing SPs; the use of SPs for stabilizing, refolding, repairing, preventing aggregation and de-aggregating macromolecules such as proteins; fusion proteins including SPs; nucleic acid constructs encoding the fusion proteins; and their uses in a variety of methods and applications.
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申请公布号 |
US2003092624(A1) |
申请公布日期 |
2003.05.15 |
申请号 |
US20020233409 |
申请日期 |
2002.09.04 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM |
发明人 |
WANG WANGXIA;PELAH DAN;ALEGRAND TAL;POUNY YEHONATHAN;MARTON IRA;WOLF AMNON;SHOSEYOV ODED;ALTMAN ARIE |
分类号 |
A01H1/00;A01H5/00;A01K67/027;A61K8/00;A61K8/64;A61K8/96;A61K38/00;A61P17/02;A61P37/06;A61Q3/02;A61Q5/00;C07K14/415;C07K16/16;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/96;C12N15/09;C12N15/29;C12N15/62;C12N15/82;C12P21/02;(IPC1-7):A61K38/16;C07H21/04;C12N5/06 |
主分类号 |
A01H1/00 |
代理机构 |
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