METHODS AND COMPOSITIONS FOR THE IDENTIFICATION, ASSESSMENT AND THERAPY OF HUMAN CANCERS

摘要

The present invention is directed to the identification of markers that can be used to determine whether cancer cells are sensitive to a therapeutic agent. Nucleic acid arrays were used to determine the level of expression of approximately 6500 nucleic acid sequences (genes) found in certain cell lines treated with a chemotherapeutic agent. Expression analysis was used to identify genes associated with sensitivity to certain chemotherapeutic agents.