发明名称 |
SELECTIVE TREATMENT OF IL-13 EXPRESSING TUMORS |
摘要 |
A method of treating tumors that express a receptor for IL-13 is disclosed. The method involves directly introducing into the tumor a cytotoxin that targets the IL-13 receptor. The cytotoxic agent can be introduced by convection-enhanced delivery through a suitable catheter or by other means. Where a convection-enhanced catheter is employed, the method involves positioning the tip of a catheter at least in close proximity to the tumor. After the catheter is positioned, it is connected to a pump which delivers the active agent through the catheter tip to the tumor. A pressure gradient from the tip of the catheter is maintained during infusion. |
申请公布号 |
WO03039600(A1) |
申请公布日期 |
2003.05.15 |
申请号 |
WO2002US36112 |
申请日期 |
2002.11.08 |
申请人 |
NEOPHARM, INC.;STRAUSS, LEWIS;PURI, RAJ |
发明人 |
STRAUSS, LEWIS;PURI, RAJ |
分类号 |
A61K45/00;A61K38/00;A61K38/16;A61K47/48;A61P35/00 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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