发明名称 Methods for treating neoplastic, angiogenic, vascular, fibroblastic, and/or immunosuppressive iregularities of the eye and/or joint via administration of combretastatin based medicaments, and iontophoretic devices for delivering combretastatin based medicaments
摘要 A method for treating neoplastic, angiogenic, vascular, fibroblastic, immunosuppressive, infectious, metabolic, and/or constitutional irregularities of the eye and/or joint of a living subject, comprising the steps of: providing a living subject, wherein the living subject includes an affected ocular and/or joint area having a neoplastic, angiogenic, fibroblastic, immunosuppressive, infectious, metabolic, and/or constitutional irregularity; providing a combretastatin-A4 based medicament, wherein the combretastatin-A4 based medicament is capable of preventing microtubule assembly, inhibiting the proliferation of endothelial, eukaryotic, and neoplastic cells, or altering their shape and function, as well as providing an anti-inflammatory effect; associating a therapeutically effective concentration of the combretastatin based medicament with the affected ocular and/or joint area of the living subject; and decreasing the neoplastic, angiogenic, vascular, fibroblastic, immunosuppressive, infectious, metabolic and/or constitutional irregularity of the eye and/or joint of the living subject.
申请公布号 US2003092774(A1) 申请公布日期 2003.05.15
申请号 US20020270273 申请日期 2002.10.11
申请人 PARKINSON THOMAS M.;SZLEK MALGORZATA;LLOYD LINDSAY B.;VOLLMER DAVID L. 发明人 PARKINSON THOMAS M.;SZLEK MALGORZATA;LLOYD LINDSAY B.;VOLLMER DAVID L.
分类号 A61K9/00;A61K31/075;A61K31/66;(IPC1-7):A61K31/075 主分类号 A61K9/00
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