| 发明名称 |
HYDRAZONO-MALONITRILES |
| 摘要 |
Hydrazono-malonitrile derivatives of the formula (I) in which R<1>, R<2>, R<3>, R<3'> and R<4> have the meanings given in Claim 1 act as phosphodiesterase IV inhibitors and can be employed for the treatment of osteoporosis, tumours, cachexia, atherosclerosis, rheumatoid arthritis, multiple sclerosis, diabetes mellitus, inflammatory processes, allergies, asthma, autoimmune diseases, myocardial diseases and AIDS.
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| 申请公布号 |
WO03039548(A1) |
申请公布日期 |
2003.05.15 |
| 申请号 |
WO2002EP11351 |
申请日期 |
2002.10.10 |
| 申请人 |
MERCK PATENT GMBH;EGGENWEILER, HANS-MICHAEL;WOLF, MICHAEL;BEIER, NORBERT;SCHELLING, PIERRE;EHRING, THOMAS |
发明人 |
EGGENWEILER, HANS-MICHAEL;WOLF, MICHAEL;BEIER, NORBERT;SCHELLING, PIERRE;EHRING, THOMAS |
| 分类号 |
A61K31/50;A61K31/501;A61K45/08;A61P1/04;A61P3/10;A61P9/04;A61P11/00;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P19/10;A61P25/00;A61P27/16;A61P29/00;A61P31/18;A61P37/08;C07D237/04;C07D403/12;(IPC1-7):A61K31/50 |
主分类号 |
A61K31/50 |
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