发明名称 |
Process for the production of alpha interferon of therapeutical degree |
摘要 |
The present invention refers to a process for the production of native alpha interferon of therapeutical degree, comprising a step of oxidizing renaturation and only one chromatographic step on cationic exchanger. Further object of the invention is native alpha interferon of therapeutical degree obtained by means of the process of the invention and corresponding to the mature form of the human alpha interferon. |
申请公布号 |
EP1310559(A1) |
申请公布日期 |
2003.05.14 |
申请号 |
EP20020024919 |
申请日期 |
2002.11.06 |
申请人 |
INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY |
发明人 |
TISMINETZKY, SERGIO GABRIEL;BARALLE, FRANCISCO ERNESTO |
分类号 |
A61K38/00;A61K38/21;C07K14/56;C12N15/21 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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