COMPOUNDS USEFUL FOR THE PREPARATION OF MEDICAMENTS WITH PHOSPHODIESTERASE IV INHIBITORY ACTIVITY.

摘要

Formula (I) compounds are described, where R1 and R2, which may be the same or different, are halogen, hydroxy, alkoxy, cycloalkoxy; X is (CH2)n-, -CO-(CH2)n-, where n is 1 or 2, or X is -CH=; R3 is -OH, -NHOH, alkoxy; Y is H, -(CH2)nCOR4, -COR4, -NHR5, where R4 is -OH, -NHOH, alkoxy, R5 is H, alkanoyl optionally substituted by halogens; n is an integer between 1 and 4; as well as processes for their preparation and their use as medicaments; particularly as selective phosphodiesterase IV inhibitors.