摘要 |
PROBLEM TO BE SOLVED: To provide a pharmaceutical preparation containing nicardipine hydrochloride at a high concentration and, nevertheless, having excellent safety and stability, effective for decreasing complicate preparation operation at the site of emergent medical treatment, keeping the quick and accurate medical treatment and avoiding the risk of microbial contamination. SOLUTION: This preparation containing nicardipine hydrochloride is produced by dissolving nicardipine hydrochloride in an acidic buffer solution at a concentration of >=2 mg/mL and filling the obtained solution having pH of 3.0-4.5 in a vessel. The oxygen concentration in the space of the vessel is <=3%.
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