摘要 |
<p>The present invention provides a compound represented by the formula (I) <CHEM> wherein ring A is benzene, cyclohexane, pyridine, piperidine or a derivative thereof, imidazole or a derivative thereof and the like, ring B is benzene, cyclohexane, pyrrole or a derivative thereof, furan, thiophene and the like, R<1>, R<2> and R<3> are each hydrogen, alkyl, halogen, hydroxyl group, alkoxy and the like, W is hydrogen, alkyl or hydroxycarbonylalkyl, X is halogen, cyano, nitro and the like, X' is hydrogen, halogen and the like, and Y is alkyl, hydroxyalkyl, hydroxycarbonylalkyl, aminoalkyl and the like, a salt thereof, and a pharmaceutical agent containing the compound. The compound of the present invention shows a superior inhibitory effect on the proliferation of activated lymphocyte and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.</p> |
申请人 |
MITSUBISHI PHARMA CORPORATION |
发明人 |
USHIO, HIROYUKI;NAITO, YOUICHIRO,C/O MITSUBISHI PHARMA CORPORATION;SUGIYAMA, NAOKI;KAWAGUCHI, TAKAFUMI,C/O MITSUBISHI PHARMA CORP.;OHTSUKI, MAKIO;CHIBA, KENJI,C/O MITSUBISHI PHARMA CORPORATION |