| 发明名称 |
USE OF CROSSLINKED CRYSTALS AS A NOVEL FORM OF ENZYME IMMOBILIZATION |
| 摘要 |
<p>A method of immobilizing an enzyme by forming crystals of the enzyme and, generally, also cross-linking the resulting crystals through the use of a bifunctional reagent; crosslinked, immobilized enzyme crystals (CLECs) made by this method; lyophilization of CLECs made by this method; lyophilized crosslinked immobilized CLECs and a method of making a desired product by means of a reaction catalyzed by a CLEC or set of CLECs.</p> |
| 申请公布号 |
EP0550450(B1) |
申请公布日期 |
2003.05.14 |
| 申请号 |
EP19910914256 |
申请日期 |
1991.07.30 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
NAVIA, MANUEL, A.;ST. CLAIR, NANCY, L. |
| 分类号 |
G01N33/66;A61K38/43;A61K38/46;C07K5/072;C12M1/34;C12M1/40;C12N9/14;C12N9/20;C12N9/36;C12N9/54;C12N9/66;C12N9/80;C12N9/82;C12N11/00;C12P21/02;C12P21/06;C12Q1/00;C12Q1/37;G01N33/531;(IPC1-7):C12N11/00 |
主分类号 |
G01N33/66 |
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