| 发明名称 |
Methods and products relating to 16-HETE analogs |
| 摘要 |
The present invention includes 16-HETE analogs which are agonists and antagonists of 16-HETE. The compositions may be formulated in pharmaceutically acceptable formulations. The invention also includes methods and products for inhibiting neutrophil adhesion and neutrophil aggregation using the 16-HETE agonists. One method of the invention involves the administration of a 16-HETE agonist in combination with a thrombolytic agent to a patient suffering from thromboembolic stroke.
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| 申请公布号 |
US6562988(B2) |
申请公布日期 |
2003.05.13 |
| 申请号 |
US20010044424 |
申请日期 |
2001.11.09 |
| 申请人 |
UNIV. VERMONT AND STATE AGRICULTURAL COLLEGE;UNIV. OF TEXAS SYSTEM BOARD OF REGENTS;NEW YORK MEDICAL COLLEGE |
发明人 |
FALCK JOHN R.;BEDNAR MARTIN M.;GROSS CORDELL E.;BALAZY MICHAEL |
| 分类号 |
A61P7/02;A61K31/18;A61K31/202;A61K31/215;A61K38/00;A61K38/49;A61P9/00;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P19/06;A61P29/00;A61P43/00;C07C49/24;C07C59/42;C07C69/732;C07C311/51;(IPC1-7):C07C233/00 |
主分类号 |
A61P7/02 |
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