Biodegradable porous polymer scaffolds for tissue engineering prepared from an effervescent mixture and its preparation

摘要

The present invention provides a method for preparing biodegradable porous polymer scaffolds for tissue engineering, comprising:a) fabricating a polymer sample from a polymer solution containing at least one biodegradable polymer and an effervescent mixture;b) effervescing the polymer sample in the presence of an effervescent medium such as an aqueous alcohol solution; andc) drying.The method for preparing biodegradable polymer scaffolds of the present invention has the advantages that the process is simple, that pore size can be easily controlled, that the problem caused by the secretion and existence of the toxic substance can be avoid by using a material harmless to human body, and that high efficiency can be achieved. In addition, biodegradable porous polymer scaffolds prepared by above method have the advantages that high porosity can be achieved and an open cell structure in which pores are interconnected is obtained.