发明名称 |
RECOMBINED ANTI-GPIIB/IIIA ANTIBODIES USED FOR INHIBITING ANGIOGENESIS |
摘要 |
The invention relates to the use of special antibodies optimised by phage- display of optimised antibodies against GPIIb/IIIa for combined inhibition o f fibrinogen to platelets and the vitronectin binding to endothelial cells for therapy and/or prophylaxis of vascular clusion. The invention also relates t o the use of said antibodies for inhibiting angiogenesis or/and for inhibiting the metastasis of tumours or/and for inhibiting intimal hyperplasia followin g vascular damage.
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申请公布号 |
CA2428649(A1) |
申请公布日期 |
2003.05.13 |
申请号 |
CA20012428649 |
申请日期 |
2001.11.20 |
申请人 |
ASAT AG |
发明人 |
ESCHER, ROBERT;BERCHTOLD, PETER |
分类号 |
A61K48/00;A61K39/395;A61P7/02;A61P9/00;A61P9/10;A61P35/04;A61P43/00;C07K16/28;(IPC1-7):A61K39/395 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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