发明名称 |
SELF-EMULSIFYING COMPOSITION FOR LIPOPHILIC COMPOUNDS |
摘要 |
FIELD: medicine, pharmacy. SUBSTANCE: invention relates to oily phase-base pharmaceutical composition. The composition comprises pyranone compound as active pharmaceutical agent that is inhibitor of retroviral protease, mixture of diglyceride and monoglyceride taken in the ratio from about 9:1 to about 6:4 (diglyceride : monoglyceride) where diglyceride and monoglyceride are esters of mono- or diunsaturated fatty acids and glycerol with chain length 16-22 carbon atoms, one or some pharmaceutically acceptable solvents and one or some pharmaceutically acceptable surface-active substances. This composition is prepared as self-emulsifying composition that provides high concentration and high oral availability of pyranone lipophilic compounds. EFFECT: valuable medicinal and pharmaceutical properties of composition. 35 cl, 3 tbl, 20 ex |
申请公布号 |
RU2203648(C2) |
申请公布日期 |
2003.05.10 |
申请号 |
RU20000104872 |
申请日期 |
1998.07.27 |
申请人 |
FARMATSIJA EHND APDZHON KOMPANI |
发明人 |
MOROZOVICH UOLTER;GAO PING |
分类号 |
C07D405/12;A61K9/107;A61K9/48;A61K31/365;A61K31/366;A61K31/44;A61K31/4433;A61K47/14;A61P31/14;A61P31/18;A61P37/04 |
主分类号 |
C07D405/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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