发明名称 MEDICINAL COMPOSITION CONTAINING CONDENSED IMIDAZOLIUM DERIVATIVE
摘要 PROBLEM TO BE SOLVED: To provide a therapeutic agent for cancers such as solid carcinomas and lymphomas. SOLUTION: This medicinal composition contains an imidazolium derivative condensed with an aryl ring or a heteroaryl ring and characterized by being substituted at its 1-position and/or 3-position with a substituted alkyl and is an antitumor agent having good antitumor activity, low toxicity and a wide margin of safety. And, thereby, the composition is useful for treatment of all solid carcinomas and lymphomas and especially useful for tumors such as cutaneous cancer, urinary bladder cancer, mastocarcinoma, uterine cancer, ovarian cancer, prostatic cancer, lung cancer, colon cancer, pancreatic cancer, renal carcinoma and stomach cancer.
申请公布号 JP2003128548(A) 申请公布日期 2003.05.08
申请号 JP20020230691 申请日期 2002.08.08
申请人 YAMANOUCHI PHARMACEUT CO LTD 发明人 MATSUHISA AKIRA;KINOYAMA ISAO;TOYOSHIMA HIROSHI;NAKAHARA TAKAHITO;TAKEUCHI MASAHIRO;OKADA MINORU
分类号 C07D235/08;A61K31/4184;A61K31/422;A61K31/4245;A61K31/427;A61K31/437;A61K31/4439;A61K31/4709;A61K31/497;A61K31/501;A61K31/506;A61P35/00;A61P43/00;C07D235/02;C07D401/06;C07D401/12;C07D403/06;C07D405/06;C07D409/06;C07D409/14;C07D413/06;C07D417/06;C07D417/14;C07D471/04;C07D495/04;(IPC1-7):A61K31/418;A61K31/424;A61K31/443;A61K31/470 主分类号 C07D235/08
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