发明名称 |
Use of ribozymes for functionating genes |
摘要 |
Methods and compositions for identifying a gene or genes associated with the generation of a specific cellular phenotype or a specific cellular response using combinatorial libraries of catalytic RNA directed against RNA sequences encoding structural or functional polypeptide motifs. The invention is exemplified by use of a combinatorial ribozyme library to target sequence in mRNAs encoding zinc finger, protein kinase and integrin motifs.
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申请公布号 |
US2003087288(A1) |
申请公布日期 |
2003.05.08 |
申请号 |
US20020244715 |
申请日期 |
2002.09.16 |
申请人 |
KECK JAMES G.;WONG JUSTIN G.P. |
发明人 |
KECK JAMES G.;WONG JUSTIN G.P. |
分类号 |
C12N15/10;C12N15/113;C12Q1/68;G01N33/53;(IPC1-7):C12Q1/68 |
主分类号 |
C12N15/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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