发明名称 HUMAN GLUCOSE-DEPENDENT INSULIN-SECRETING CELL LINE
摘要 Disclosed herein is a novel cell line of human pancreatic cells that secrete insulin in a glucose-dependent manner. The cell line comprises pancreatic cells, such as PANC-1 cells, which are transfected so as to express IDX-1 and cultured in GLP-1. The cell line may be used to investigate the function and development of pancreatic cells, as well as to test the efficacy of drugs that stimulate insulin secretion.
申请公布号 WO03012084(B1) 申请公布日期 2003.05.08
申请号 WO2002US23857 申请日期 2002.07.25
申请人 CEDARS-SINAI MEDICAL CENTER 发明人 PERFETTI, RICCARDO
分类号 C12N5/071;(IPC1-7):C12N5/06 主分类号 C12N5/071
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