发明名称 |
Methods and compositions for treating gastric disorders with optically pure (-) pantoprazole |
摘要 |
Methods and compositions are disclosed utilizing optically pure (-) pantoprazole for the treatment of ulcers in humans while substantially reducing the concomitant liability of adverse effects associated with the racemic mixture of pantoprazole. The optically pure (-) isomer is also useful for the treatment of gastroesophageal reflux. (-) Pantoprazole is an inhibitor of H+ release and is therefore useful in the treatment of other conditions related to gastric hypersecretion such as Zollinger-Ellison Syndrome.
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申请公布号 |
US2003086968(A1) |
申请公布日期 |
2003.05.08 |
申请号 |
US20020256518 |
申请日期 |
2002.09.26 |
申请人 |
SEPRACOR INC. |
发明人 |
GRAY NANCY M. |
分类号 |
C07D401/12;A61K31/44;A61K31/4427;A61K31/4439;A61P1/04;(IPC1-7):A61K31/443 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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