| 发明名称 |
PROTOBERBERINE DERIVATIVES WHICH INHIBIT ACTIVITY OF THE MITOGEN-ACTIVATED PROTEIN KINASE |
| 摘要 |
The present invention relates to protoberberine derivatives which inhibit the activity of mitogen-activated protein kinase. More specifically, the present invention is directed to protoberberine derivatives which inhibit the activity of Wis1 and Spc1 kinase in intracellular signal transduction cascade wherein mitogen-activated protein kinase (MAPK) is involved. |
| 申请公布号 |
EP1307198(A1) |
申请公布日期 |
2003.05.07 |
| 申请号 |
EP20010941270 |
申请日期 |
2001.06.14 |
| 申请人 |
HANWHA CHEMICAL CORPORATION |
发明人 |
SONG, KI-WON;SONG, KI-WON;JANG, MYOUNG-JIN;PAIK, YOUNG-KI;KIM, JUNG-HO, |
| 分类号 |
A61K31/473;C07D455/03;A61K31/4375;A61K31/4741;A61P31/10;A61P35/00;A61P43/00;(IPC1-7):A61K31/473 |
主分类号 |
A61K31/473 |
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