发明名称 |
TETRAMERIC ANTIBODY COMPLEXES FOR BLOCKING NON-SPECIFIC LABELING OF ANTIGENS |
摘要 |
A method for preventing or inhibiting non-specific binding reactions between a detection reagent and an antigen in an immunological assay is described. The method involves using tetrameric antibody complexes that can bind to the antigen and are comprised of two monoclonal antibodies of a first animal species linked to two monoclonal antibodies of a second animal species that can bind the antibodies of the first animal species. Preferably , the antigen is an Fc Receptor and the method reduces the binding of a detection antibody with Fc receptors present on the surface of many cells.</ SDOAB>
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申请公布号 |
CA2411392(A1) |
申请公布日期 |
2003.05.07 |
申请号 |
CA20022411392 |
申请日期 |
2002.11.07 |
申请人 |
STEMCELL TECHNOLOGIES INC. |
发明人 |
LANSDORP, PETER MICHAEL;WOGNUM, ALBERTUS WERNERUS |
分类号 |
A61K39/395;C07K16/28;G01N33/53;(IPC1-7):A61K39/395 |
主分类号 |
A61K39/395 |
代理机构 |
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地址 |
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