发明名称 Bicyclic amino acids
摘要 Compounds of the formula Iin whichX, Y, Z, R1, R2, R3, R4, R5, R7, R8, R11, m and n have the meanings stated in claim 1, and their physiologically acceptable salts can be used as integrin inhibitors, in particular for the prophylaxis and treatment of circulatory disorders, for thrombosis, myocardial infarct, coronary heart disease, arteriosclerosis, osteoporosis, for pathological processes maintained or propagated by angiogenesis, and in tumour therapy.
申请公布号 US6559144(B2) 申请公布日期 2003.05.06
申请号 US20010842004 申请日期 2001.04.26
申请人 MERCK PATENT GESELLSCHAFT MIT 发明人 DIEFENBACH BEATE;GOODMAN SIMON L.;MAERZ JOACHIM;RADDATZ PETER;RIPPMANN FRIEDRICH;WIESNER MATTHIAS
分类号 C07D265/36;C07D319/20;C07D405/12;C07D413/12;(IPC1-7):A61K31/536;A61K31/357;C07D319/14;C07D215/00;C07D365/34 主分类号 C07D265/36
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