| 摘要 |
<p>A novel injectable aqueous miscible composition of cyclo-oxygenase-2 inhibitors such as nimesulide which comprises: a) cyclooxygenase inhibitors belonging to the group of NSAIDS; b) one or more alkyl amides, alkyl sulphoxides or pyrrolidones; c) one or more glycols or combination thereof; d) 0 to 20% water; and a process for preparing this composition. The analgesic injectable composition is very useful in mammals particularly in humans for the treatment of acute painful conditions like post operative trauma, pain associated with cancer, sports injuries, migraine headache, neurological pain, pain associated with sciatica and spondylitis. For these indications some modified route of administrations may also be construed.</p> |
