NEUROPILIN AS A NOVEL THERAPEUTIC TARGET FOR MODULATION OF IMMUNE REPONSES

摘要

The invention relates to methods that enable the identification of modulators of immune responses mediated by immune effective cells, especially of the initiation of primary immune responses, and to methods for treating and / or preventing diseases or pathologic conditions associated with or controlled by said immunes responses. More specifically, it concerns methods for identifying compounds that modulate the selective interaction between cells implicated in the immune responses and/or that induce or inhibit the recruitment of semaphorin by neuropilin receptor and that are useful for modulating the immune responses mediated by immune effective cells.