| 摘要 |
<p>A compound represented by the general formula (I): (I) (wherein R1 is hydroxy, etc.; R2 is optionally substituted lower alkyl, etc.; R3 is hydrogen, etc.; R4 is optionally substituted allylene, etc.; R5 is -C≡C-, etc.; and R6 and R7 each is hydrogen, lower alkoxy, etc.), an optically active isomer thereof, a prodrug thereof, or a pharmaceutically acceptable salt or solvate of any of these; and an inhibitor against MMP-2, 8, 9, 12, and/or 13 which contains the compound as an active ingredient.</p> |
