发明名称 |
Composite biodegradable polymer scaffold |
摘要 |
A polymer scaffold is provided comprising an extensively interconnected macroporous network. The polymer scaffold embodies macropores having a diameter in a range of 0.5-3.5 mm, and preferably in a range of about 1.0-2.0 mm. The polymer scaffold is prepared using a novel process which advantageously combines the techniques of particulate leaching and phase inversion to render a process that provides amplified means by which to control the morphology of the resulting polymer scaffold. The polymer scaffold has utility in the area of tissue engineering, particularly as a scaffold for both in vitro and in vivo cell growth. The polymer scaffold may be produced using pure polymer or alternatively a composite material may be formed consisting of a macroporous polymer scaffold and osteoclast-resorbable calcium phosphate particles with a binding agent binding the calcium phosphate particles to the polymer scaffold.
|
申请公布号 |
US2003082808(A1) |
申请公布日期 |
2003.05.01 |
申请号 |
US20020134652 |
申请日期 |
2002.04.30 |
申请人 |
GUAN LIMIN;HOLY CHANTAL E.;SHOICHET MOLLY S.;DAVIES JOHN E. |
发明人 |
GUAN LIMIN;HOLY CHANTAL E.;SHOICHET MOLLY S.;DAVIES JOHN E. |
分类号 |
A61L27/18;A61L27/46;A61L27/56;C12N5/00;C12N5/02;C12N5/077;(IPC1-7):C12N5/00 |
主分类号 |
A61L27/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|