REMOVAL OF BACTERIAL ENDOTOXIN IN A PROTEIN SOLUTION BY IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY
摘要
The present invention relates to the purification of polypeptides and the removal of endotoxin via immobilized metal affinity chromatography (IMAC). More specifically, the invention relates to methods for removing bacterial endotoxin in a protein solution. In specific embodiments, the invention relates to the elimination of endotoxin from Moraxella catarrhalis outer membrane proteins.
申请公布号
WO02083710(A3)
申请公布日期
2003.05.01
申请号
WO2002US10937
申请日期
2002.04.05
申请人
WYETH HOLDINGS CORPORATION;SUNDBERG, RHONDA, LUNT;HOPFER, ROBERT, LEONARD