| 摘要 |
PURPOSE: Provided are novel pyrazine derivatives or salts thereof, a pharmaceutical composition containing the same, and a production intermediates thereof. CONSTITUTION: A pyrazine derivative is represented by the general formula(1), wherein R1 represents a hydrogen atom or a halogen atom; R2 represents a hydrogen atom or a protected or unprotected monophosphoric, diphosphoric or triphosphoric acid group; R3, R4, R5 and R6 which may be the same or different represent a hydrogen atom, a halogen atom, an azido group, a substituted or unsubstituted, protected or unprotected hydroxyl or amino group or R4 and R6, taken conjointly, represent a bonding unit; A represents an oxygen atom or a methylene group; n represents 0 or 1; and Y represents an oxygen atom, a sulfur atom or an NH group,or a Salt thereof provided that the case in which R1 represents a hydrogen atom or a halogen atom; R2 represents a hydrogen atom; R3 and R5 represent a hydrogen atom; R4 and R6 represent a substituted or unsubstituted, protected or unprotected hydroxyl group; A represents an oxygen atom; n represents 0; and Y represents an oxygen atom is excluded. |
