摘要 |
A method to directly detect eukaryotic or prokaryotic genomic DNA is disclosed. The invention relates to a method for printing, immobilizing, hybridizing and directly detecting a target nucleic acid sequence in a sample of methylated genomic DNA. Additionally, this invention provides a system for the detection of a target nucleic acid sequence including a flat substrate to bind methylated DNA in discrete patterns and a plurality of labeled target binding probes specific for a target nucleic acid sequence.
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