Disclosed are methods for treating cancer comprising administering a xenotypic monoclonal antibody and a chemotherapeutic drug to a patient suffering from cancer. Also disclosed is a method for inducing a host immune response in a patient against a multi-epitopic in vivo tumor antigen in present in the host serum, which antigen does not elicit a host immune response, comprising administering to the patient a chemotherapeutic drug and a composition comprising a binding agent that specifically binds to a first epitope on the antigen and allowing the binding agent to form a binding agent/antigen pair, wherein a host immune response is elicited against a second epitope on the antigen.
申请公布号
WO03034977(A2)
申请公布日期
2003.05.01
申请号
WO2002IB05794
申请日期
2002.10.28
申请人
ALTAREX CORP.;SCHULTES, BIRGIT, C.;NICODEMUS, CHRISTOPHER, F.;NOUJAIM, ANTOINE
发明人
SCHULTES, BIRGIT, C.;NICODEMUS, CHRISTOPHER, F.;NOUJAIM, ANTOINE