摘要 |
Leptin, leptin analogs, and leptin derivatives are used to treat patients with lipodystrophy. Leptin is effective against lipodystrophy conditions for both genetic and acquired forms of the disease. A therapeutically effective amount of leptin can be administered in a variety of ways, including in a vector comprising nucleic acid sequences encoding leptin. Methods of the present invention contemplate administration of leptin, leptin analogs, and leptin derivatives to patients having approximately 4 ng/ml or less before treatment. |
申请人 |
AMGEN, INC.;DEPAOLI, ALEX, M.;ORAL, ELIF, ARIOGLU;TAYLOR, SIMEON, I.;GARG, ABHIMANYU |
发明人 |
DEPAOLI, ALEX, M.;ORAL, ELIF, ARIOGLU;TAYLOR, SIMEON, I.;GARG, ABHIMANYU |