摘要 |
<p>Novel Anti-inflammatory Androstane DerivativesThere are provided compounds of formula (I) wherein R1 represents O, S or NH;R2 represents -C(=O)-aryl or -C(=O)-heteroaryl;R3 represents hydrogen, methyl (which may be in either the ( or ( configuration) or methylene; R4 and R5 are the same or different and each represents hydrogen or halogen; and represents a single or a double bond;and salts and solvates thereof;process for preparing them, compositions containing them and their use in therapy.</p> |