Animal model of allergies

摘要

The present invention provides an animal model for studying allergic reactions to allergens. The animal is sensitized to a selected antigen by administering the antigen itself or a nucleic acid encoding the antigen. Preferred antigens are anaphylactic antigens. The sensitized animal can then be used to screen for compounds which may help to prevent, ameliorate, or cure allergic conditions in humans. A method of sensitizing an animal as well as a method and system for screening chemical compounds is also disclosed.