Progestogen receptor polypeptides, transgenic cells in which genes encoding said polypeptides are introduced and method for detecting disruptors for progestogens by using said transgenic cells

摘要

A polypeptide having an amino acid sequence (a) or (b) given below. (a) a polypeptide having an amino acid sequence shown by amino acid Nos. 1 to 689 in Sequence Listing No. 2 and (b) a polypeptide which has activity of a progestogen receptor and which is a derivative obtained by way of deletion, substitution, addition or insertion of a part of the amino acid sequence in the above (a). Corresponding DNA gene and transgenic cell as well as a method for detecting a disruptor using this transgenic cell are also disclosed.