The invention relates to a method for transiently immortalizing cells according to which immortalization proteins are introduced into the cells from outside. The invention also relates to a method for producing cells according to which organ-related cells are transiently immortalized by the exogenous supply of immortalization proteins and are remortalized after their expansion. The invention further relates to the cells produced according to the inventive method, to the use of said cells for producing a transplant and to the immortalization proteins used in the method.
申请公布号
WO03035884(A2)
申请公布日期
2003.05.01
申请号
WO2002EP11200
申请日期
2002.10.07
申请人
HEART BIOSYSTEMS GMBH;KUEPER, JAN-HEINER;MEYER, RALPH;MEYER-FICCA, MIRELLA;KUHN, ANNE
发明人
KUEPER, JAN-HEINER;MEYER, RALPH;MEYER-FICCA, MIRELLA;KUHN, ANNE