INTRAVASCULAR DEVICE FOR TREATMENT OF HYPERTENSION

摘要

Some aspects include a mechanical pump (3) which is placed in the renal artery (4) by means of a percutaneous catheter (6), surgical implantation, or other appropriate means. This pump increases blood flow through the renal artery to the kidney (12). This increased bloodflow is perceived at the level of the macula densa as increased sodium delivery to the macula densa and the juxtaglomerular apparatus, resulting in suppression of renin production from the juxtaglomerular apparatus, with consequent reduction in angiotensin II production and aldosterone levels. This decreased aldosterone and decreased angiotensin II production lead to a reduction in blood pressure.