发明名称 |
REMEDIES FOR INTERSTITIAL PNEUMONIA, METHOD OF CONSTRUCTING ANIMAL MODEL OF THIS DISEASE AND SCREENING METHOD WITH THE USE OF THE SAME |
摘要 |
Remedies for interstitial pneumonia containing, as the active ingredient, one or more members selected from among IL-18 and IL-2 inhibitors. A method of constructing an animal model of the above disease and a screening method with the use of the same. The above remedies inhibit the excessive expression of the functions of IL-18/IL-2 participating in the onset of interstitial pneumonia, and thus exert a therapeutic effect. The above animal model exhibits clinical findings closely similar to human cases and thus enables accurate screening of a drug expected as clinically efficacious.
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申请公布号 |
WO0180891(A8) |
申请公布日期 |
2003.05.01 |
申请号 |
WO2001JP03467 |
申请日期 |
2001.04.23 |
申请人 |
NIPPON ORGANON K. K.;HOSHINO, TOMOAKI |
发明人 |
HOSHINO, TOMOAKI |
分类号 |
A61K38/00;A61K38/20;A61P11/00;(IPC1-7):A61K45/00;A61K38/55;A61K39/395;A01K67/00;G01N33/15 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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