摘要 |
The invention relates to bi-cyclic peptides with the structure corresponding to the general formula (I) : wherein X1, X2, X3, X4, X5 and X6, the same or different from one another represent a NR'CO or CONR' group where R' is H or C1-C5 alkyl ; Y represents an alcoxy group selected from NRCO-CONR or SS, wherein R is H or C1-C3 alkyl ; at least one of R1, R2, R3, and R4 groups, the same or different from one another is hydrophilic and the remaining groups are hydrophobic; m and n, the same or different from one another are each an integer number from 1 to 4, and to a pharmaceutical composition containing the same.
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