Chemiluminescent substrates for neuraminidase, assays for detection of neuraminidase and kits therefor

摘要

The present invention discloses chemiluminescent 1,2-dioxetane substrates capable of reacting with a neuraminidase to release optically detectable energy. These 1,2-dioxetanes have the general formula:wherein Z isand the variables are selected so as to induce decomposition of said dioxetane accompanied by chemiluminescence where Z is cleaved by neuraminidase present.