METHOD AND DEVICE FOR PRODUCING NONCELLULAR ERYTHROCYTE- SUBSTITUTE

摘要

FIELD: medicine; medical engineering. SUBSTANCE: method involves injecting cross-linked, polymerized, tetramer-free pyridoxy-blended hemoglobin solution to human patients in the amount reaching 5 l. Leukocytes and blood platelets are removed from blood. Erythrocytes are washed and subjected to lysis. Stroma admixtures and stroma are removed by means of filtration and heat treatment. Desoxyhemoglobin form is produced. Pyridoxylation and polymerization, cleaning and condensing and deoxigenation are carried out next to it. EFFECT: no toxicity; considerable half-life period of 15 h order. 18 cl, 6 dwg, 1 tbl