| 发明名称 |
CARBOCYANINE DYES FOR TANDEM, PHOTODIAGNOSTIC AND THERAPEUTIC APPLICATIONS |
| 摘要 |
Novel tumor specific phototherapeutic and photodiagnostic agents are disclosed. The compounds consist of a carbocyanine dye for visualization, photosensitizer for photodynamic treatment, and tumor receptor-avid peptide for site-specific delivery of the probe and phototoxic agent to diseased tissues. A combination of these elements takes full advantage of the unique and efficient properties of each component for an effective patient care management. |
| 申请公布号 |
CA2463994(A1) |
申请公布日期 |
2003.04.24 |
| 申请号 |
CA20022463994 |
申请日期 |
2002.10.07 |
| 申请人 |
MALLINCKRODT CHEMICAL, INC. |
发明人 |
RAJAGOPALAN, RAGHAVAN;ACHILEFU, SAMUEL I.;BUGAJ, JOSEPH E.;DORSHOW, RICHARD B. |
| 分类号 |
A61K38/00;A61K41/00;A61K49/00;A61P9/10;A61P35/00;C07K7/06;C09B23/01;(IPC1-7):A61B10/00;A61B5/00;A61B8/00 |
主分类号 |
A61K38/00 |
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