NEUTROKINE-ALPHA AND NEUTROKINE-ALPHA SPLICE VARIANT
摘要
The present invention relates to nucleic acid molecules encoding Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides, including soluble forms of the extracellular domain. Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to antibodies or portions thereof that specifically bind Neutrokine-alpha and/or Neutrokine-alphaSV and diagnostic and therapeutic methods using these antibodies. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders using the compositions of the invention.
申请公布号
WO03033658(A2)
申请公布日期
2003.04.24
申请号
WO2002US32910
申请日期
2002.10.16
申请人
HUMAN GENOME SCIENCES, INC.;YU, GUO-LIANG;EBNER, REINHARD;NI, JIAN;ROSEN, CRAIG, A.;LAIRD, MICHAEL, W.;ULLRICH, STEPHEN
发明人
YU, GUO-LIANG;EBNER, REINHARD;NI, JIAN;ROSEN, CRAIG, A.;LAIRD, MICHAEL, W.;ULLRICH, STEPHEN