| 发明名称 |
ANTISENSE ANTIVIRAL AGENT AND METHOD FOR TREATING SSRNA VIRAL INFECTION |
| 摘要 |
This invention provides antisense antiviral compounds and methods of their u se in inhibition of growth of viruses of the picornavirus, calicivirus, togavir us and flavivirus families, as in treatment of a viral infection. The antisense antiviral compounds are substantially uncharged oligomers having a targeting base sequence that is substantially complementary to a viral target sequence which spans the AUG start site of the first open reading frame of the viral genome.
|
| 申请公布号 |
CA2463641(A1) |
申请公布日期 |
2003.04.24 |
| 申请号 |
CA20022463641 |
申请日期 |
2002.10.16 |
| 申请人 |
AVI BIOPHARMA, INC. |
发明人 |
SKILLING, DOUGLAS E.;IVERSEN, PATRICK L.;SMITH, ALVIN W.;STEIN, DAVID A. |
| 分类号 |
G01N33/53;A61K31/7105;A61K31/712;A61K31/7125;A61K38/00;A61K48/00;A61P31/14;C12N15/09;C12N15/113;C12Q1/68;G01N33/566;G01N33/569;(IPC1-7):A61K31/712;A61K31/537;A61K31/675;C12Q1/70;A61K31/706 |
主分类号 |
G01N33/53 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
