PH RESPONSIVE BIODEGRADABLE POLYLACTIC ACID DERIVATIVES FORMING POLYMERIC MICELLES AND USES THEREOF FOR POORLY WATER SOLUBLE DRUG DELIVERY

摘要

Polylactic acid derivatives capable of forming micelles in an aqueous soluti on with a pH of 4 or above, having one terminal carboxyl group. The polylactic acid derivatives may be applied as a drug delivery system in various forms since poorly water soluble drugs can be entrapped inside the micelles.